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Claudiu T Supuran Selected Research

Dandruff

12/2020Activation studies of the β-carbonic anhydrases from Malassezia restricta with amines and amino acids.
1/2020Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions.
7/2019Anion Inhibition Profile of the β-Carbonic Anhydrase from the Opportunist Pathogenic Fungus Malassezia Restricta Involved in Dandruff and Seborrheic Dermatitis.
5/2019Cloning, Purification, and Characterization of a β-Carbonic Anhydrase from Malassezia restricta, an Opportunistic Pathogen Involved in Dandruff and Seborrheic Dermatitis.
1/2018Natural Polyphenols Selectively Inhibit β-Carbonic Anhydrase from the Dandruff-Producing Fungus Malassezia globosa: Activity and Modeling Studies.
12/2017Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates.
1/2017Inhibition of Malassezia globosa carbonic anhydrase with phenols.
1/2017Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa.
12/2016A new procedure for the cloning, expression and purification of the β-carbonic anhydrase from the pathogenic yeast Malassezia globosa, an anti-dandruff drug target.
3/2016Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from Malassezia globosa with amines and amino acids.
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Claudiu T Supuran Research Topics

Disease

614Neoplasms (Cancer)
05/2024 - 11/2002
89Glaucoma
01/2024 - 02/2002
75Hypoxia (Hypoxemia)
11/2023 - 06/2004
42Neoplasm Metastasis (Metastasis)
12/2023 - 01/2010
40Breast Neoplasms (Breast Cancer)
02/2024 - 03/2005
35Epilepsy (Aura)
12/2023 - 01/2007
32Obesity
03/2024 - 02/2004
26Neuralgia (Stump Neuralgia)
12/2023 - 04/2015
22Infections
03/2024 - 07/2002
21Alzheimer Disease (Alzheimer's Disease)
03/2024 - 01/2002
21Carcinogenesis
10/2023 - 11/2005
16Malaria
11/2023 - 01/2008
15Dehydration (Water Stress)
05/2023 - 10/2003
15Pain (Aches)
01/2023 - 01/2007
14Chagas Disease (American Trypanosomiasis)
12/2022 - 02/2013
13Acidosis
12/2022 - 01/2008
13Arthritis (Polyarthritis)
10/2022 - 01/2016
13Dandruff
12/2020 - 04/2012
12Pathologic Processes
12/2023 - 08/2006
12Retinitis Pigmentosa (Pigmentary Retinopathy)
12/2019 - 01/2017
11Rheumatoid Arthritis
01/2023 - 09/2003
11Seizures (Absence Seizure)
01/2023 - 01/2007
11Carcinoma (Carcinomatosis)
01/2021 - 08/2006
10Weight Loss (Weight Reduction)
12/2022 - 03/2005
8Inflammation (Inflammations)
11/2023 - 01/2007
8Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 10/2017
8Prostatic Neoplasms (Prostate Cancer)
01/2023 - 03/2005
8Colonic Neoplasms (Colon Cancer)
12/2021 - 04/2009
8Melanoma (Melanoma, Malignant)
12/2020 - 10/2012
8Hypertension (High Blood Pressure)
05/2017 - 01/2008
7Nervous System Diseases (Neurological Disorders)
11/2023 - 03/2003
6Tuberculosis (Tuberculoses)
02/2024 - 01/2007
6Triple Negative Breast Neoplasms
12/2023 - 01/2019
6Edema (Dropsy)
01/2022 - 01/2016
5Neurodegenerative Diseases (Neurodegenerative Disease)
11/2023 - 01/2016
5Cognitive Dysfunction
12/2022 - 01/2016
5Communicable Diseases (Infectious Diseases)
12/2022 - 02/2004
5Squamous Cell Carcinoma of Head and Neck
10/2022 - 12/2016

Drug/Important Bio-Agent (IBA)

472Carbonic Anhydrases (Carbonic Anhydrase)IBA
05/2024 - 02/2003
413Protein Isoforms (Isoforms)IBA
05/2024 - 08/2003
237SulfonamidesIBA
04/2024 - 10/2002
168EnzymesIBA
04/2024 - 02/2003
163IsoenzymesIBA
05/2024 - 02/2002
123Carbonic Anhydrase IXIBA
04/2024 - 03/2003
84Carbonic Anhydrase InhibitorsIBA
03/2024 - 03/2003
56BenzenesulfonamidesIBA
04/2024 - 04/2005
49Acetazolamide (Diamox)FDA LinkGeneric
05/2024 - 03/2003
43ZincIBA
06/2023 - 05/2003
34Proteins (Proteins, Gene)FDA Link
12/2022 - 06/2004
32SLC-0111IBA
02/2024 - 03/2016
31CoumarinsIBA
11/2023 - 08/2010
29Antineoplastic Agents (Antineoplastics)IBA
10/2023 - 01/2004
27Anticonvulsants (Antiepileptic Drugs)IBA
12/2022 - 03/2003
26coumarinIBA
04/2024 - 08/2010
16Bicarbonates (Hydrogen Carbonate)IBA
12/2022 - 11/2002
15Doxorubicin (Adriamycin)FDA LinkGeneric
02/2024 - 01/2012
14AnionsIBA
07/2019 - 11/2002
13Protons (Proton)IBA
12/2022 - 06/2004
12AcidsIBA
12/2023 - 06/2014
12Oxygen (Dioxygen)IBA
11/2023 - 06/2004
12Biomarkers (Surrogate Marker)IBA
08/2023 - 06/2007
12DiureticsIBA
12/2022 - 08/2006
12Amino AcidsFDA Link
10/2021 - 08/2007
11sulfamic acid (ammonium sulfamate)IBA
11/2019 - 12/2003
10Topiramate (Topamax)FDA LinkGeneric
03/2024 - 03/2005
10Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
03/2024 - 01/2004
10Carbon DioxideIBA
01/2023 - 06/2004
10AminesIBA
12/2022 - 08/2007
10Anti-Bacterial Agents (Antibiotics)IBA
12/2022 - 03/2005
10dorzolamide (Trusopt)FDA LinkGeneric
04/2020 - 03/2003
9Benzene (Benzole)IBA
12/2023 - 03/2008
9Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2023 - 04/2015
8Carbonic Anhydrase IIIBA
04/2024 - 06/2009
8LigandsIBA
04/2024 - 04/2014
8Zonisamide (Zonegran)FDA LinkGeneric
03/2024 - 01/2007
8carbonic anhydrase XIIIBA
11/2022 - 06/2013
8ProdrugsIBA
06/2022 - 12/2013
8Carboxylic AcidsIBA
01/2022 - 12/2014
8SulfanilamideFDA Link
01/2022 - 02/2004
7Reactive Oxygen Species (Oxygen Radicals)IBA
03/2024 - 11/2005
7SaltsIBA
02/2024 - 04/2007
7Anti-Obesity Agents (Antiobesity Drugs)IBA
01/2021 - 08/2006
7Enzyme Inhibitors (Inhibitors, Enzyme)IBA
09/2017 - 02/2009
7Sulfhydryl Compounds (Thiols)IBA
01/2016 - 05/2005
7Antiglaucoma AgentsIBA
07/2012 - 08/2006
6Matrix Metalloproteinases (MMPs)IBA
02/2024 - 09/2003
6Antimalarials (Antimalarial Agents)IBA
11/2023 - 01/2007
6Monoclonal AntibodiesIBA
01/2023 - 01/2012
6Celecoxib (Celebrex)FDA Link
04/2020 - 01/2015
6Hydro-Lyases (Dehydratases)IBA
03/2020 - 01/2007
6Transcription Factors (Transcription Factor)IBA
01/2018 - 11/2006
6CarbohydratesIBA
10/2014 - 11/2006
5MethazolamideFDA LinkGeneric
03/2024 - 03/2003
5pyrazoleIBA
01/2023 - 12/2014
5PiperazineIBA
01/2023 - 08/2009
5CaspasesIBA
10/2022 - 09/2003
5SaccharinIBA
08/2022 - 03/2014

Therapy/Procedure

113Therapeutics
04/2024 - 01/2002
17Radiotherapy
02/2023 - 07/2005
16Drug Therapy (Chemotherapy)
12/2023 - 05/2003